Hold the Date
- CALERIE Working Group: First Tuesday at 3pm, Network members meeting
- Led by Dr. William Kraus
- Monthly, the first Tuesday at 3pm EST
- Updates on ongoing projects, discussions of complex physiology, review of data and analytics
- Please contact calerie@duke.edu for calendar invitations and more information.
Past Summits
- 2025 CALERIE Summit
The 2025 CALERIE Summit, held from April 28-30, 2025, was a multi-day event focused on advancing research in caloric restriction and aging. View Summit Schedule
Watch Summit Video Recordings Here
It began with an evening registration and welcome dinner featuring a presentation by Bill Kraus, followed by a keynote on macronutrients ...
12 + hours
Seminar Video Footage
100 +
Publications
1 billion+
Data points
Highlights of Samples and Data
Samples and Data may be requested, case studies reviews and examples of past and future proposals
Featured Investigators
01/13/2026
Dr. Rozalyn Anderson is a Vilas Distinguished Professor in the Department of Medicine in the Division of Geriatrics and Gerontology at the University of Wisconsin-Madison School of Medicine and Public Health. Dr. Anderson is Director of the NIH/NIA sponsored Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging (WiNSC), Director of the Metabolism of Aging program, Director of the Biology of Aging and Age-Related Diseases T32 training program, and Associate Director of Research in the Geriatric Research, Education, and Clinical Center at the William S Middleton Memorial Veterans Hospital.
She is a Fellow and former Chair of the Biological Sciences section of the Gerontological Society of America and a Fellow and former President of the American Aging Association. She a recipient of the Nathan Shock New Investigator Award (GSA), the Biological Mechanisms in Aging Award (Glenn Foundation), the Breakthroughs in Gerontology Award (AFAR), and the Denham Harman Award (American Aging Association).
Dr. Anderson’s group recently published the following manuscript:
Clark JP, Rhoads TW, McIlwain SJ, Polewski MA, Pavelec DM, Colman RJ, Anderson RM. Caloric Restriction Reprograms Adipose Tissues in Rhesus Monkeys. Aging Cell. 2025 Dec;24(12):e70254. doi: 10.1111/acel.70254. Epub 2025 Oct 3. PMID: 41042069; PMCID: PMC12686577.
08/01/2025
Sridevi (Sri) Krishnan, M.Sc., PhD is a nutritional glycobiologist who studies how diet influences the development of age-related metabolic diseases. With a foundation in nutritional biology and recent expertise in glycobiology—the science of glycosylation, glycoproteins, and glycans—Sri works in a specialized field focused on how dietary and systemic glycans impact health, aging, and disease.
As part of the molecular working group in the CALERIE2 research network, Sri contributed to a pilot study showing that calorie restriction reduces both established and novel glycomic biomarkers of aging, including those found in plasma, IgG, and complement C3. Her current research explores how calorie restriction affects the glycome of alpha-1 acid glycoprotein (AGP), a highly glycosylated protein involved in immune response and metabolic regulation. AGP has recently been identified as a leptin receptor agonist, but the role of its glycosylation in modulating function remains unknown. This study is the first to evaluate AGP glycosylation before, during, and after a long-term dietary intervention.
Future research will expand this work to assess glycomic biomarkers of aging and longevity in obese populations, the full CALERIE2 cohort, and other U.S.-based studies.
Additional projects in Sri’s lab include developing oligosaccharide-based synbiotic interventions to improve blood glucose in individuals with type 2 diabetes, and creating GenAI-powered tools to make “Food as Medicine” strategies accessible to communities experiencing food and nutrition insecurity.
08/19/2025
Dr. Falkenhain is a postdoctoral researcher at Pennington Biomedical Research Center. Her research focuses on cross-disciplinary investigations into human (patho)physiology, particularly how nutritional exposures (e.g., diets varying in macronutrients, signaling molecules such as ketones or GLP-1) affect cardiometabolic health. With training in both basic and clinical science, she aims to understand individual responses to these interventions by linking clinical outcomes to underlying mechanisms. Dr. Falkenhain currently works on two main projects: the NIH-funded Nutrition for Precision Health study aiming to develop algorithms that predict individual responses to diet, and her postdoctoral fellowship funded by the American Heart Association to explore how GLP-1RA affect gut-brain nutrient sensing.
